About the CRE-RHAI


The Centre of Research Excellence in Reducing Healthcare Associated Infections (CRE-RHAI) is an NHMRC funded research collaboration focused on developing and investigating innovative and cost-effective strategies to reduce the incidence of healthcare associated infections in Australia. The CRE-RHAI is led by Professor Nick Graves and brings together a diverse group of experts from clinical and academic fields to work together on research that will translate into improved infection control decisions at clinical and policy level.

The CRE-RHAI research areas include:
• Modelling the transmission dynamics of multi-resistant organisms
• Assessing the impact of antimicrobial stewardship programs
• The cost-effectiveness of infection control interventions, such as environmental cleaning in hospitals
• The factors that drive decision making in healthcare infection control
• Improving the surveillance of healthcare associated infections in Australia

Put simply, the CRE-RHAI is a dedicated team of researchers who are passionate about finding solutions to the problem of healthcare associated infections.

Why concentrate on cost-effectiveness?

The purpose of cost-effectiveness research is to show the value for money of competing strategies, such as using antibiotic coated catheters versus quality improvement bundles to reduce central line associated blood stream infections. Cost-effectiveness analysis takes into account not only how well each intervention works to prevent infections, but also how much each prevented infection costs.  Using cost-effectiveness information allows the decision maker to respond to the problem of scarce resources which is a major challenge facing all health services.

What are Healthcare Associated Infections?

Healthcare Associated Infections, or HAI, are just that – infections which are associated with healthcare. They include things such as surgical site infections, blood stream infections from central catheters, or infections contracted during a visit to hospital. HAI were previously called nosocomial, or hospital acquired infections. Commonly known HAI are infections with MRSA (Methicillin-resistant Staphylococcus aureus) and Clostridium difficile.




The CRE-RHAI works closely with government agencies and professional bodies in infection control, and collaborates with industry partners on specific events or projects. Current partners of the CRE-RHAI include: 


Australian Commission on Safety and Quality in Health Care

We work with the ACSQHC to put cost-effectiveness information about infection control on the agenda of policy makers. Our research will help hospitals meet ACSQHC accreditation standard 3 (Preventing and Controlling Healthcare Associated Infections) in the most cost-effective manner possible. 


Australasian College for Infection Prevention and Control

We work with the ACIPC to disseminate research findings to our clinical stakeholders and to consult and engage with infection control practitioners through the College’s wide networks.




We are based within the Institute of Health and Biomedical Innovation at the Queensland University of Technology, although our research has a national focus and our Investigators are based around Australia and the world.



We have close ties with the Australian Centre for Health Service Innovation, which operates to build research capability and capacity in health services, and to deliver innovative solutions to health service challenges.



We are funded by an NHMRC Centre of Research Excellence (CRE) grant, with a funding period from 2012 to 2017. The award of this grant offers the CRE-RHAI an extraordinary opportunity to perform vital research on reducing healthcare associated infections. Grant number 1030103.

The contents of this website are solely the responsibility of the Administering Institution (QUT), a Participating Institution, or individual authors, and do not reflect the views of the NHMRC.